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Developing treatments for chronic diseases
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Journal Articles

Single-dose pharmacokinetics of different oral sodium nitrite formulations in diabetes patients.

Greenway FL, Predmore BL, Flanagan DR, Giordano T, Qiu Y, Brandon A, Lefer DJ, Patel RP, Kevil CG.
Diabetes Technol Ther. 2012 Jul;14(7):552-60. doi: 10.1089/dia.2011.0291. Epub 2012 Apr 2.

Sodium nitrite in patients with peripheral artery disease and diabetes mellitus: safety, walking distance and endothelial function.

Mohler ER 3rd, Hiatt WR, Gornik HL, Kevil CG, Quyyumi A, Haynes WG, Annex BH.
Vasc Med. 2014 Feb;19(1):9-17. doi: 10.1177/1358863X13515043. Epub 2013 Dec 20.

Inorganic nitrite therapy: historical perspective and future directions.

Kevil CG, Kolluru GK, Pattillo CB, Giordano T.
Free Radic Biol Med. 2011 Aug 1;51 (3):576-93. Epub 2011 May 4. Review.

Review Focus on Inorganic Nitrite and Nitrate in Cardiovascular Health and Disease.

Kevil CG, Lefer DJ.
Cardiovasc Res. 2011 Feb 15;89(3):489-91. Epub 2010 Dec 23.

Inorganic nitrite and chronic tissue ischaemia: a novel therapeutic modality for peripheral vascular diseases.

Pattillo CB, Bir S, Rajaram V, Kevil CG.
Cardiovasc Res. 2011 Feb 15;89(3):533-41. Epub Sep 16. Review.

Genome expression profiling and network analysis of nitrite therapy during chronic ischemia: Possible mechanisms and interesting molecules.

Pattillo CB, Fang K, Pardue S, Kevil CG.
Nitric Oxide. 2010 Feb 15;22(2):168-79. Epub 2009 Dec 4.

Nitrate and nitrite in biology, nutrition and therapeutics.

Lundberg JO, Gladwin MT, Ahluwalia A, Benjamin N, Bryan NS, Butler A, Cabrales P, Fago A, Feelisch M, Ford PC, Freeman BA, Frenneaux M, Friedman J, Kelm M, Kevil CG, Kim-Shapiro DB, Kozlov AV, Lancaster JR Jr, Lefer DJ, McColl K, McCurry K, Patel RP, Petersson J, Rassaf T, Reutov VP, Richter-Addo GB, Schechter A, Shiva S, Tsuchiya K, van Faassen EE, Webb AJ, Zuckerbraun BS, Zweier JL, Weitzberg E.
Nat Chem Biol. 2009 Dec;5(12):865-9.

Preserving vessel function during ischemic disease: new possibilities of inorganic nitrite therapy.

Kevil CG, Patel RP.
Expert Rev Cardiovasc Ther. 2008 Oct;6(9):1175-9.

Drug discovery: a lifeline for suffocating tissues.

Mazzone M, Carmeliet P.
Nature. 2008 Jun 26;453(7199):1194-5.

Chronic sodium nitrite therapy augments ischemia-induced angiogenesis and arteriogenesis.

Kumar D, Branch BG, Pattillo CB, Hood J, Thoma S, Simpson S, Illum S, Arora N, Chidlow JH Jr, Langston W, Teng X, Lefer DJ, Patel RP, Kevil CG.
Proc Natl Acad Sci U S A. 2008 May 27;105(21):7540-5.